What is another name for Sofosbuvir?
Sofosbuvir (tradename Sovaldi) is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV).
What is the drug Sofosbuvir used for?
Sofosbuvir is used along with ribavirin (Copegus, Rebetol, Ribasphere, others) and sometimes another medication (peginterferon alfa [Pegasys]) to treat certain types of chronic hepatitis C (an ongoing viral infection that damages the liver) in adults.
Does Sofosbuvir cure hep C?
Sofosbuvir is effective for treating infection with HCV genotype 1,2,3, or 4, and in clinical trials, 50% to 90% of individuals treated with the drug cleared the hepatitis C virus from their blood.
What disorder does sofosbuvir and velpatasvir Epclusa treat?
Generic Name: sofosbuvir-velpatasvir This medication is a combination of sofosbuvir and velpatasvir and is used to treat chronic (long-lasting) hepatitis C, a viral infection of the liver.
Is sofosbuvir a biologic?
In December of 2013, Sovaldi (sofosbuvir) and Olysio (simeprevir) were approved by the United States Food and Drug Administration. The chemical composition of both Sovaldi and Olysio are different than traditional medications in that they are biologics.
Is sofosbuvir a chain terminator?
Although sofosbuvir has a 3′ hydroxyl group to act as a nucleophile for an incoming NTP, a similar nucleotide analogue, 2′-deoxy-2′-α-fluoro-β-C-methylcytidine, is proposed to act as a chain terminator because the 2′ methyl group of the nucleotide analogue causes a steric clash with an incoming NTP.
How does Sofosbuvir and Velpatasvir work?
Velpatasvir is in a class of antiviral medications called HCV NS5A replication complex inhibitors. The combination of sofosbuvir and velpatasvir works by stopping the virus that causes hepatitis C from spreading inside the body.
Can sofosbuvir be used alone?
Sofosbuvir should not be used alone. Use only the medications prescribed for you. Do not share your medicine with other people. Sofosbuvir is sometimes used in people who also have HIV, or people who have liver cancer and are going to have a liver transplant. This medicine is not a treatment for HIV or AIDS.
Can hep C come back after successful treatment?
It’s possible, but rare, for hepatitis C infection to reappear after apparently successful treatment. Relapses usually occur in the first few months after blood testing to confirm that the virus is no longer detectable. Sometimes, however, a relapse becomes evident much later.
Is sofosbuvir and velpatasvir the same as Epclusa?
Epclusa (sofosbuvir / velpatasvir) is available as a generic medication and may be significantly cheaper compared to the brand version. Unless there is a specific reason you need the brand, the generic medication will be a better value.
How do you take sofosbuvir and velpatasvir?
The combination of sofosbuvir and velpatasvir comes as a tablet to take by mouth. It is taken usually with or without food once a day for 12 weeks. Take sofosbuvir and velpatasvir at around the same time every day.