What is CSF Baricity?

Baricity refers to the density of a substance compared to the density of human cerebrospinal fluid. Baricity is used in anesthesia to determine the manner in which a particular drug will spread in the intrathecal space.

Why bupivacaine is heavy?

Bupivacaine Heavy is hyperbaric and its initial spread in the intrathecal space is affected by gravity. Due to the small dose, the intrathecal spread results in a relatively low concentration, and the duration of local anaesthesia tends to be relatively shorter.

What is Barbotage spinal?

[ bär′bə-täzh′ ] n. The production of spinal anesthesia in which a portion of the anesthetic solution is injected into the cerebral spinal fluid, which is then aspirated into the syringe and a second portion of the contents of the syringe is injected.

How dense is CSF?

Results: The mean CSF density in the study population was 1.00059 +/- SD 0.00020. In men of all ages, the mean CSF density was 1.00067 +/- 0.00018 g. ml-1; in postmenopausal women 1.00060 +/- 0.00015 g.

What is baricity of bupivacaine?

Isobar bupivacaine is not commonly used for spinal anesthesia, but could be a good alternative for obstetric patients due to lower complications than the hyperbaric solution. 8. Besides to volume, the concentration and dose of local anesthetic, as well as the baricity of solution might affect spinal block profile.

What is hyperbaric bupivacaine?

Bupivacaine is an amide local anaesthetic used in hyperbaric and isobaric forms. These are administered intrathecally into the spine to provide regional anaesthesia for caesarean section. Several trials have compared hyperbaric and isobaric bupivacaine but none have conclusively shown the benefit of either.

Is bupivacaine and Marcaine the same?

Bupivacaine, marketed under the brand name Marcaine among others, is a medication used to decrease feeling in a specific area. In nerve blocks, it is injected around a nerve that supplies the area, or into the spinal canal’s epidural space.

What is the swirl of CSF called?

The turbulence and swirling CSF flow in the third ventricle (10), should have some functional significance in terms of CSF signaling, which can be referred to as the CSF paracrine system.

How dense is the human brain?


Density (kg/m³) Average Minimum
Brain 1046 1041
Brain (Grey Matter) 1045 1039
Brain (White Matter) 1041 1040
Breast Fat 911 812

What is the density of gold?

Density of Gold is 19.3g/cm3. Typical densities of various substances are at atmospheric pressure. Density is defined as the mass per unit volume. It is an intensive property, which is mathematically defined as mass divided by volume:

What is the coefficient of compressibility of gold?

Compressibility (also known as the coefficient of compressibility is a measure of the relative volume change of a fluid or solid as a response to a pressure (or mean stress) change. Atomic mass of Gold is 196.9665 u. The atomic mass is the mass of an atom.

What is the density of gold at STP?

Gold – Density – Au Element Gold Element Category Transition Metal Phase at STP Solid Atomic Mass [amu] 196.9665 Density at STP 19.3 g/cm3

What is the concentration of gold in the ocean?

The world’s oceans contain gold. Measured concentrations of gold in the Atlantic and Northeast Pacific are 50–150 femtomol /L or 10–30 parts per quadrillion (about 10–30 g/km 3 ). In general, gold concentrations for south Atlantic and central Pacific samples are the same (~50 femtomol/L) but less certain.