What is the CDH4 gene?

Cadherin-4 is a protein that in humans is encoded by the CDH4 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail.

What is Cadherin-4?

From Wikipedia, the free encyclopedia Cadherin-4 is a protein that in humans is encoded by the CDH4 gene. This gene is a classical cadherin from the cadherin superfamily.

What is the desintoxicación de toxinas?

El objetivo de la desintoxicación, también llamada «eliminación de toxinas» o «tratamiento de abstinencia», es permitirte suspender el consumo de la droga adictiva de la forma más rápida y segura posible. Para algunas personas, puede ser seguro someterse al tratamiento de abstinencia de manera ambulatoria.

What is the role of CDH4 in triple-negative breast cancer?

High CDH4 expression is associated with triple-negative breast cancer. CDH4 overexpression activates c-Jun via the JNK pathway, while CDH4 knockdown suppresses both tumor xenograft growth and lung colonization. CDH4 may play a negative role in the growth and metastasis of salivary adenoid cystic carcinoma via co-expression with E-cadherin.

What is the role of CDH4 in epithelial cells?

R-cadherin induces cell motility when expressed in epithelial cells, and this increased motility is dependent upon Rho GTPase activity. CDH4 may act as a tumor suppressor gene in human gastrointestinal tumors and can potentially be used as an early diagnostic marker for gastrointestinal tumorigenesis

How does circRNA EPB41L2 regulate CDH4?

CircRNA EPB41L2 inhibits tumorigenicity of lung adenocarcinoma through regulating CDH4 by miR-211-5p. Expression and Prognostic Significance of Cadherin 4 (CDH4) in Renal Cell Carcinoma.