What is the function of indapamide tablet?

Indapamide, a ‘water pill,’ is used to reduce the swelling and fluid retention caused by heart disease. It also is used to treat high blood pressure. It causes the kidneys to get rid of unneeded water and salt from the body into the urine.

How does indapamide affect the kidneys?

Indapamide inhibits sodium absorption in the kidneys, causing the sodium to be excreted into the urine. As sodium is excreted, it takes with it fluid from the blood, decreasing the amount of fluid volume in the veins and arteries, thus, lowering the blood pressure.

Does indapamide cause hyponatremia?

Conclusions: Indapamide can cause both severe hypokalemia and hyponatremia. The predominant clinical features can be a result of severe hyponatremia. The latter can have diverse clinical presentations and may be mistaken for SIADH.

What is the best time to take indapamide?

How to use Indapamide. Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. If you take this drug too close to bedtime, you may need to wake up to urinate. It is best to take this medication at least 4 hours before your bedtime.

Is indapamide and natrilix same?

The name of your medicine is NATRILIX. NATRILIX contains the active ingredient indapamide which belongs to a group of medicines called chlorosulfamoyl diuretics (a type of “fluid” or “water” tablet).

When do you take indapamide?

It’s best to take indapamide in the morning. If you take indapamide too late in the day you may have to get up during the night to go to the toilet. Swallow the tablets whole with a drink of water. You can take indapamide with or without food.

Can you take vitamin D with indapamide?

Using indapamide together with cholecalciferol can cause your blood calcium levels to become too high. Contact your doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. You may need a dose adjustment or special test if you use both medications.

What are the long term side effects of indapamide?

If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.

What is the pharmacology of indapamide 88?

8.1 Pharmacology. Indapamide is an antihypertensive and a diuretic. It contains both a polar sulfamoyl chlorobenzamide moiety and a lipid- soluble methylindoline moiety. Indapamide bears a structural similarity to the triazide diuretics which are known to decrease vascular smooth muscle reactivity.

Does indapamide have a vascular effect?

Indapamide is a new antihypertensive diuretic agent indicated for the treatment of hypertension and edema. Indapamide shows an alteration in vascular reactivity to calcium and other agonists, suggesting the possibility of a direct vascular effect. The drug is recommended in doses of 2.5 to 5 mg once a day.

How does indapamide interact with potassium?

Indapamide is an indole derivative of chlorosulphonamide and a sulfamyl diuretic with antihypertensive activity. Indapamide may interact directly with the subunits of delayed rectifier potassium channels, thereby blocking both slow and rapid K+ (IKs and IKr) currents through the channels.

What are the different forms of indapamide?

Form and composition. Indapamide is available generically as 1.25 mg and 2.5 mg non-scored tablets. It is now also available in SR (sustained release) form.