What kind of seizures does Wellbutrin cause?

A physician considering WELLBUTRIN for the management of a patient’s first episode of depression should be aware that the drug may cause generalized seizures in a dose-dependent manner with an approximate incidence of 0.4% (4/1,000).

What happens if you OD on bupropion?

In severe toxic doses it can cause coma, hypotension, multiple seizures, QRS widening, QTc prolongation, status epilepticus, and ventricular dysrhythmias [2]. Seizure due to intentional or unintentional overdose is among the most commonly reported toxic effect of bupropion [3–6].

How much Wellbutrin can cause death?

Serious toxicity can be expected with doses > 6 g, and fatalities usually involve doses > 9 g.

What class of drug is bupropion?

Bupropion is in a class of medications called antidepressants. It works by increasing certain types of activity in the brain.

Will Wellbutrin make me have a seizure?

Seizures are a rare but serious side effect of Wellbutrin that some people experience. The risk of having a seizure while taking Wellbutrin is higher in people who: have an underlying condition that causes seizures.

Can bupropion overdose cause brain damage?

Conclusion: By unclear mechanisms, massive bupropion overdose can produce a clinical picture consistent with brain death with complete recovery after clearance of drug.

Can bupropion cause Parkinson’s?

Bupropion is an atypical antidepressant usually claimed to be a norepinephrine and a dopamine reuptake inhibitor. However, its action on the dopamine system remains controversial. Acute dystonia, dyskinesia, and parkinsonian symptoms associated with bupropion have occasionally been reported in white patients.

What is the highest amount of Wellbutrin you can take?

Wellbutrin SR:

  • Typical starting dosage: 150 mg per day, taken as a single dose in the morning.
  • Dosage increases: After 3 days, the dosage may be increased to 300 mg per day, taken as 150 mg twice daily. Wait at least eight hours between doses.
  • Maximum dosage: 400 mg per day, taken as 200 mg twice daily.

What are the most common side effects of bupropion?

Common side effects Headache, weight loss, dry mouth, trouble sleeping (insomnia), nausea, dizziness, constipation, fast heartbeat, and sore throat. These will often improve over the first week or two as you continue to take the medication.

What can you not take with bupropion?

Do not use an MAO inhibitor within 14 days before or 14 days after you take bupropion. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Do not take bupropion to treat more than one condition at a time.