When was Mellaril invented?

Thioridazine (Melleril/Mellaril) is a piperidine phenothiazine similar to chlorpromazine that is taken by mouth and was developed and tested soon after chlorpromazine in the 1950s (Bain 1998).

When was Mellaril discontinued?

Thioridazine is the generic name of the drug and comes in tablet form. The brand name for thioridazine, Mellaril, was discontinued in 2005 due to potential long-term effects, but it is still available in the generic version.

Why was thioridazine discontinued?

Novartis has announced a worldwide discontinuation of the drug Melleril (Mellaril in the US and Canada, and also known under the generic name thioridazine), due to concerns that the drug causes increased risk of cardiac arrhythmias and sudden death.

What was Mellaril used for?

This medication is used to treat certain mental/mood disorders (such as schizophrenia). This medication helps you to think more clearly, feel less nervous, and take part in everyday life. It can also help prevent suicide in people likely to harm themselves and reduce aggression and the desire to hurt others.

Is Thorazine still used today?

The brand name Thorazine is discontinued in the U.S. Generic forms may be available.

What is the oldest antipsychotic drug?

Chlorpromazine. Chlorpromazine is a phenothiazine antipsychotic that is a dopamine D2 receptor antagonist. It was the first conventional antipsychotic developed and is still in wide use for treatment of schizophrenia.

Is Mellaril discontinued?

The Mellaril brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

Is Paraldehyde still used?

Paraldehyde is used to treat certain convulsive disorders. It also has been used in the treatment of alcoholism and in the treatment of nervous and mental conditions to calm or relax patients who are nervous or tense and to produce sleep.

What class of drug is Mellaril?

Mellaril (thioridazine HCl) is an anti-psychotic medication in the phenothiazine class used to treat psychotic disorders such as schizophrenia, and is usually given after other medications have been tried without successful treatment of schizophrenia.

What should I know about Mellaril before using it?

While using Mellaril, you may need frequent blood tests. Your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG). If you need surgery, tell the surgeon ahead of time that you are using Mellaril.

Is there a generic version of Mellaril?

The Mellaril brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

Does Mellaril cause torsades?

Mellaril has been shown to prolong the QTc interval in a dose related manner, and drugs with this potential, including Mellaril, have been associated with Torsades de pointes type arrhythmias and sudden death.

How many times a day can you take Mellaril?

This medication comes in tablet form and is typically taken 2 to 4 times a day, with or without food. Common side effects of Mellaril include dry mouth, blurry vision, constipation, nausea, vomiting, diarrhea, and drowsiness.