What are the laboratory findings in HUS?

Blood tests can also reveal a low platelet count, low red blood cell count or a higher than normal level of creatinine, a waste product normally removed by your kidneys. Urine test. This test can detect abnormal levels of protein, blood and signs of infection in your urine. Stool sample.

What is HUS ultrasound?

The sonographic appearance of kidneys in patients presenting with acute renal failure due to hemolytic-uremic syndrome (HUS) was evaluated and compared with that in an age-matched control series. In nine patients with HUS, the renal cortex was typically hyperechogenic and the renal pyramids appeared sonolucent.

Is Bun elevated in HUS?

Diagnosis of hemolytic uremic syndrome Fragmented or deformed RBCs seen under a microscope. Decreased platelet count. Elevated blood urea nitrogen (BUN) and creatinine due to decreased kidney function.

What is a typical HUS?

Typical HUS (ie, STEC-HUS) follows a gastrointestinal infection with STEC, whereas aHUS is associated primarily with mutations or autoantibodies leading to dysregulated complement activation.

Which findings indicate hemolytic uremic syndrome?

The characteristic pathologic findings of hemolytic-uremic syndrome (HUS) are occlusive lesions of the arterioles and small arteries and consequent tissue microinfarctions. In HUS, the lesions are usually limited to the kidneys, whereas the lesions are more widespread in thrombotic thrombocytopenic purpura (TTP).

What is HUS diagnosis?

What is hemolytic uremic syndrome? HUS is a rare but serious disease that affects the kidneys and blood clotting functions of infected people. Infection with HUS causes destruction of red blood cells, which can then cause kidney failure. HUS occurs as a complication of a diarrheal infection (usually E.

How is atypical HUS diagnosed?

Diagnosing aHUS is complicated by the fact that it is more difficult to establish without a family history of the disorder. The diagnostic criteria associated with aHUS are hemolytic anemia (anemia in the presence of broken red blood cells), low platelet count (thrombocytopenia) and kidney dysfunction.

What is the classic triad associated with hemolytic uremic syndrome?

Hemolytic uremic syndrome (HUS) is a clinical syndrome characterized with the triad of microangiopathy hemolytic anemia, thrombocytopenia and acute renal damage. It is one of the most common causes of acute renal damage in children.

How is uremia diagnosed?

Creatinine and BUN blood tests help your provider confirm a diagnosis of uremia. These tests check your blood for high levels of waste products. They also used to estimate your glomerular filtration rate (eGFR). This rate measures your kidney function.

How do I know if I have HUS?

Symptoms of HUS include vomiting, bloody diarrhea (loose stool/poop), stomach pain, fever, chills, and headache. As infection progresses, persons may experience fatigue, weakness, fainting, bruising, and paleness.

How is renal length measured in an ultrasound?

An accurate measurement of renal length depends upon obtaining a truly midline renal image in the sagittal plane. In ultrasound image (a) the right kidney is in the true midline as noted by the medial discontinuity of the renal parenchyma . This represents the hiatus through which the renal vessels and collecting system enter and exit (arrow).

What is a horseshoe kidney on an ultrasound?

Horseshoe kidney: A transverse ultrasound view across the midline showing the isthmus across the aorta. A sagittal ultrasound view of the isthmus of a horseshoe kidney. A rare fusion anomaly that results in the complete fusion of both right and left kidneys during their ascent from the sacral region.

How does Hus affect the kidneys?

In HUS the tiny filter units in the kidneys known as glomeruli become clogged with platelets and damaged red blood cells. This leads to problems with the kidney’s ability to filter and eliminate waste products. How is HUS treated? HUS is generally treated with medical care in the hospital.

What are the components of a renal ultrasound report?

The generation of the ultrasound documentation is a critical component of all renal ultrasound examinations and is routinely audited by other entities for clinical information, appropriateness of the examination, and reimbursement. The report has four components: indications, equipment, findings, and impression. Indications