What is a rotor stator homogenizer?
Rotor-stator homogenizers consist of a fast-spinning inner rotor with a stationary outer sheath (stator) to homogenize samples through mechanical tearing, shear fluid forces, and / or cavitation (the rapid forming and collapsing of bubbles).
How does a rotor stator homogenizer work?
Rotor stator homogenizers use shear force to process samples. The rotor component is a metal shaft that rotates at fast speeds within the stator (a metal casing that remains stationary). The rotor rotation results in a suction effect that pulls the sample into the high-shear environment between the stator and rotor.
What is a tissue homogenizer?
Tissue homogenization is the process of breaking down tissue structure to form a suspension or emulsion of tissue solids, proteins and fluid, creating a suspension of tissue cellular fragments obtained after the tissue is homogenized, lysed, sonicated or digested [1].
What is a rotor stator system?
The rotor‒stator system is designed to overcome the interfacial tension to enlarge the interfaces by input of high mechanical energy with the rotor‒stator system. A suspension is a heterogeneous material composition consisting of a liquid containing finely distributed solids.
How does a homogenizer work?
A homogenizer works by breaking or subdividing the dispersed components into smaller particles and then distributing them evenly throughout the mixture. The action created by the homogenizer continuously disrupts the formation of large particles due to immiscibility and precipitation.
What does a motor stator do?
In an electric motor, the stator provides a magnetic field that drives the rotating armature; in a generator, the stator converts the rotating magnetic field to electric current. In fluid powered devices, the stator guides the flow of fluid to or from the rotating part of the system.
What is the function of homogenizer?
Abstract. Homogenizers function as mixers that reduce particle size or force immiscible liquids to mix. Pressure imparted on a product by the homogenizer is largely determined by pump pressure or flow diversion through valves and nozzles.
What is the principle of homogeniser?
The homogenizer principle of operation is a rather simple one: spread the laser energy, typically concentrated at the center of the beam, by scattering the beam so that it overlaps itself multiple times, creating a beam with a larger divergence angle than the original beam, but whose energy is spread more uniformly.
How many types of homogenizers are there?
There are a number of different types of homogenizer. The three most common are rotor/stator generators (or colloid mills), high pressure (or piston pump) models, and sonic disruptors. Rotor/stator homogenizers are the most common type.
Why do you homogenize the tissue?
Biological tissue is routinely homogenized in order to extract various analytes (proteins, DNA, RNA, small molecules, etc.).
What is rotor-stator mixers?
Rotor-stator mixers are single-shaft mixers with an impeller rotating in close proximity to a stationary housing. They are used to rapidly break apart solid particles in a liquid, or to emulsify a liquid into liquids. The impeller or rotor mechanically imparts high-shear forces to the ingredients.
What is a Rotor Stator Homogenizer?
Rotor Stator Homogenizers. Rotor-stator homogenizers consist of a fast-spinning inner rotor with a stationary outer sheath (stator) to homogenize samples through mechanical tearing, shear fluid forces, and / or cavitation (the rapid forming and collapsing of bubbles). Rotor-stators are broadly capable of homogenizing a wide variety…
How many samples can I homogenize with a rotor-stator?
Most rotor-stators homogenize a single sample at a time, although some high-throughput models and continuous / in-line models are available. Keep in mind: rotor-stator homogenizers require a probe to operate and not all rotor-stators come with a probe.
What is a mortar and pestle homogenizer?
Mortar and pestle homogenizers consist of a hard, blunt object (the pestle) which is used to grind the sample against a solid container (the mortar). Used in life science applications, there are often called tissue grinders.
How to choose the right tissue homogenizer for your application?
While many tissue applications are deal with small (mg-scale) pieces of tissue, ensure that you select a homogenizer which is capable of processing the sample sizes which you intend to use. Also, remember that larger samples generally take more time to homogenize than smaller samples.