What is considered a low IgM level?
There are no other underlying immunodeficiencies. Serum IgM levels are less than 10–15 mg/dl in infants and children and less than 20–30 mg/dl in adults. Other immunoglobulin levels and T cell immunity are usually normal.
What is normal IgM range?
The normal range for IgM in the blood is around 40 – 250 mg/dL (milligrams per deciliter).
What happens if IgM is low?
Similar to other PI disorders, individuals with SIGMD have frequent infections caused by bacteria, fungi, and protozoa. The frequent infections happen because, without healthy IgM or working/functional IgM, the person is not able to develop strong IgG responses.
Can low IgM cause fatigue?
Fatigue Is Common in Immunoglobulin G Subclass Deficiency and Correlates With Inflammatory Response and Need for Immunoglobulin Replacement Therapy. Purpose: Individuals with immunoglobulin G deficiency (IgGsd) often complain of fatigue.
Is low IgG serious?
People with IgG deficiency are more likely to get infections. When your body feels it is under attack, it makes special proteins called immunoglobulins or antibodies. These antibodies are made by the plasma cells. They are let loose throughout the body to help kill bacteria, viruses, and other germs.
What is a good IgM level?
Reference Range
| Age | IgA | IgM |
|---|---|---|
| 9 – 12 years | 0.70 – 2.50 | 0.50 – 1.80 |
| 12 – 15 years | 0.80 – 2.80 | 0.50 – 1.90 |
| 16 – 45 years | 0.80 – 2.80 | 0.50 – 1.90 |
| Over 45 years | 0.80 – 4.00 | 0.50 – 2.00 |
What is a low IgG level?
An IgG deficiency is a health problem in which your body doesn’t make enough Immunoglobulin G (IgG). People with IgG deficiency are more likely to get infections. When your body feels it is under attack, it makes special proteins called immunoglobulins or antibodies. These antibodies are made by the plasma cells.
Why is my immunoglobulin low?
Low levels of immunoglobulins mean your immune system isn’t working as well as it should. This can be caused by: Medicines that weaken your immune system, such as steroids. Diabetes complications.
What is the normal range of Covid antibodies?
“You’re more protected at 2,500 than at 1,000. It’s up to you and your risk of exposure, your risk of severe disease, all of those things together, to know whether you need to be at greater than 1,000 or if 1,000 is fine for you.”
What is considered low IgG level?
Serum IgG levels reduced by more than 2 SDs below the mean, accompanied by deficiencies in IgA and/or IgM, suggest common variable immunodeficiency. Usually the IgG level is less than 400 mg/dL; 70% of patients will have very low or absent IgA content.