What is the normal range of ceruloplasmin?
The normal range for adults is 14 to 40 mg/dL (0.93 to 2.65 µmol/L). Normal value ranges may vary slightly among different laboratories.
What is a normal ceruloplasmin test?
The normal range for a ceruloplasmin serum test is 20 to 35 milligrams per deciliter (mg/dL). If you have Wilson disease, your ceruloplasmin level will probably be below 10 mg/dL. Low ceruloplasmin might also mean Menkes disease.
What is a high ceruloplasmin level?
What does high ceruloplasmin mean? High ceruloplasmin levels could mean you have irregularly high levels of copper. This can be a sign of: Heart disease.
What is the level of ceruloplasmin in Wilson’s disease?
Approximately 90% of all patients with Wilson disease have ceruloplasmin levels of less than 20 mg/dL (reference range, 20-40 mg/dL). (Ceruloplasmin is an acute phase reactant and may be increased in response to hepatic inflammation, pregnancy, estrogen use, or infection.)
What is a normal copper level in blood?
The normal range for total copper in the blood is 85 to 180 micrograms per deciliter (mcg/dL). A low amount of copper could mean that you have: Kidney disease. A nutritional deficiency.
What blood test shows Wilson’s disease?
Tests and procedures used to diagnose Wilson’s disease include: Blood and urine tests. Blood tests can monitor your liver function and check the level of a protein that binds copper in the blood (ceruloplasmin) and the level of copper in your blood.
What is low ceruloplasmin level?
A lower than normal level of ceruloplasmin may mean your body is not able to use or eliminate copper properly. It can be a sign of: Wilson disease. Menkes syndrome. Liver disease.
What is the normal blood level of copper?
What is ceruloplasmin in blood test results?
Ceruloplasmin is a copper-containing enzyme that plays a role in the body’s iron metabolism. This test measures the amount of ceruloplasmin in the blood.
Why is ceruloplasmin high in inflammation?
Ceruloplasmin is an acute phase reactant and due to result of elevated gene transcription in hepatocytes, the concentration in serum is increased during inflammation, infection and trauma which are mediated by cytokines.
What is a high copper level?
Copper toxicity means you have more than 140 mcg/dL of copper in your blood.
What is ceruloplasmin?
Ceruloplasmin is a protein made in your liver. Ceruloplasmin stores and carries the mineral copper around your body. Ceruloplasmin carries 65% to 90% of the copper found in blood. Copper is vital to many processes in your body. These include building strong bones and making melanin. But having too much copper in your body can be toxic.
What is the normal range for ceruloplasmin?
The normal range for a ceruloplasmin serum test is 20 to 35 milligrams per deciliter (mg/dL). If you have Wilson disease, your ceruloplasmin level will probably be below 10 mg/dL.
What color is ceruloplasmin in serum?
A solution of ceruloplasmin is blue, and excess in serum may give the serum a greenish hue. Each ceruloplasmin molecule can contain 6 to 8 copper atoms.  Issues of Concern Ceruloplasmin is not a routine value measured in standard labs.
What is the PMC code for ceruloplasmin?
PMC 319888. PMID 6940148. Kingston IB, Kingston BL, Putnam FW (Apr 1980). “Primary structure of a histidine-rich proteolytic fragment of human ceruloplasmin. I. Amino acid sequence of the cyanogen bromide peptides”.