What does eggNOG-Mapper do?

eggNOG-mapper is a tool for functional annotation of large sets of sequences based on fast orthology assignments using precomputed clusters and phylogenies from the eggNOG database. Orthology assignment is ideally suited for functional inference.

What is eggNOG annotation?

eggNOG (evolutionary genealogy of genes: Non-supervised Orthologous Groups) is a public resource in which thousands of genomes are analyzed at once to establish orthology relationships between all their genes.

What is an ortholog?

Orthologs are genes in different species that evolved from a common ancestral gene by speciation, and, in general, orthologs retain the same function during the course of evolution. Identification of orthologs is a critical process for reliable prediction of gene function in newly sequenced genomes.

What are clusters of orthologous groups?

The Clusters of Orthologous Groups (COGs) of proteins were generated by comparing the protein sequences of complete genomes. Each cluster contains proteins or groups of paralogs from at least three lineages. The current COG database contains both prokaryotic clusters (COGs) and eukaryotic clusters (KOGs).

What is in alcoholic eggNOG?

Eggnog is typically made with rum, brandy or bourbon, and Brown likes to start with a combination of dark rum and cognac. But there’s no need to go premium; he recommends using an affordable, high-proof VS cognac. The higher alcohol level will cut through the sweetness of the rest of the ingredients.

How do you make German eggNOG?


  1. 1 cup milk.
  2. 1 cup cream.
  3. 3/4 cup sugar.
  4. 1 vanilla bean, split lengthwise.
  5. 5 large egg yolks.
  6. 1/2 cup vodka.
  7. 1/2 cup brandy.

What is the difference between paralog and ortholog?

“By definition, orthologs are genes that are related by vertical descent from a common ancestor and encode proteins with the same function in different species. By contrast, paralogs are homologous genes that have evolved by duplication and code for protein with similar, but not identical functions.”

What is Xenologs?

xenolog (plural xenologs) (genetics) A type of ortholog where the homologous sequences are found in different species because of horizontal gene transfer.

What does KEGG stand for?

Kyoto Encyclopedia of Genes and Genomes
Abstract. KEGG (Kyoto Encyclopedia of Genes and Genomes) is a knowledge base for systematic analysis of gene functions, linking genomic information with higher order functional information.

How many cog categories are there?

This is approximately 54% of the analyzed eukaryotic gene products. The COGs and KOGs are classified into functional classifications….Categories.

A RNA processing and modification
E Amino Acid metabolis and transport
F Nucleotide metabolism and transport
G Carbohydrate metabolism and transport
H Coenzyme metabolis

What is the best alcoholic eggnog?

How do you make classic eggnog?

Classic Eggnog. Ingredients. Directions. Whisk the eggs, egg yolk and sugar in a bowl until combined. Heat the milk and 1/2 cup heavy cream in a medium saucepan over medium heat until steaming; do not boil. Remove from the heat. Whisk 1 cup of the hot milk mixture into the egg mixture, then whisk the egg mixture back into the saucepan.

What is the rating of eggnog from scratch?

Eggnog from Scratch Eggnog from Scratch Rating: 4.67 stars 40 Ratings 5star values:33 4star values:4 3star values:2 2star values:0 1star values:1 Read Reviews Add Review 40 Ratings 38 Reviews 3 Photos

Is eggnog supposed to be thick?

I have been making this eggnog ever since finding it in a Home Economics Cookbook “So- you are ready to cook” by Mary Ann Duffie. To the reviewer who gave a low rating because it was not “thick”, this is NOT meant to be “thick”, if you like it that thick, try using sweetened condensed milk.