What is HSP 70 antibody?
HSP 70 Antibody (3A3) is a high quality monoclonal HSP 70 antibody (also designated HSPA1A antibody, HSP72 antibody or heat shock protein A (Hsp70) antibody) suitable for the detection of the HSP 70 protein of mouse, rat and human origin.
Is sensorineural hearing loss an autoimmune disease?
Autoimmune sensorineural hearing loss (SNHL) is a rare clinical entity characterized by a progressive fluctuating bilateral asymmetric SNHL that develops over several weeks to months. Vestibular symptoms, tinnitus and aural fullness are present in up to 50% of patients.
How do you test for AIED?
The diagnosis of AIED requires (1) a hearing test confirming bilateral, new-onset, progressive sensorineural hearing loss, (2) the appropriate symptom time-course as determined by patient history, and (3) an MRI Brain with Internal Auditory Canal protocol that finds no evidence of retrocochlear mass lesions.
Can monoclonal antibodies cause hearing loss?
These findings suggest that KHRI-3 antibody has an effect on hearing that is secondary to damage to the organ of Corti and loss of outer hair cells. Our results have important implications for antibody-mediated mechanisms of hearing loss and provide an animal model in which to study this phenomenon.
What autoimmune disease affects your ears?
Autoimmune inner ear disease (AIED), is a rare disease that happens when your body’s immune system mistakenly attacks your inner ear. It can cause dizziness, ringing in your ears, and hearing loss. Less than 1% of the 28 million Americans who have hearing loss have it because of AIED.
What are the symptoms of autoimmune inner ear disease?
The symptoms of AIED are sudden hearing loss in one ear progressing rapidly to the second ear. The hearing loss can progress over weeks or months. Patients may feel fullness in the ear and experience vertigo. In addition, a ringing, hissing, or roaring sound in the ear may be experienced.
What autoimmune disease causes Meniere’s disease?
An autoimmune disease, such as diabetes, lupus, or rheumatoid arthritis. Had a head injury, especially if it involved your ear. Had a viral infection of the inner ear.
What are the symptoms of autoimmune ear disease?
Is vertigo an autoimmune disease?
Vertigo and other audiovestibular symptoms may be the first manifestation of an autoimmune disease and if correctly addressed could significantly contribute to early diagnosis of the underlying autoimmune disease.
What’s the difference between vertigo and Meniere’s?
Quick movements that trigger episodes of vertigo include sitting up, turning around, or turning over in bed. Meniere’s Disease: Meniere’s disease is a condition in which fluid builds up in the inner ear. Individuals with Meniere’s disease experience sudden episodes of vertigo that may last several hours.