What is the primary action of metoclopramide?
Metoclopramide increases gastric emptying by decreasing lower esophageal sphincter (LES) pressure. It also exerts effects on the area postrema of the brain, preventing and relieving the symptoms of nausea and vomiting.
What type of drug is metoclopramide?
This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used as a short-term treatment (4 to 12 weeks) for ongoing heartburn when the usual medicines do not work well enough. It is used mostly for heartburn that occurs after a meal or during the daytime.
Which of the following patients is metoclopramide contraindicated?
Metoclopramide is contraindicated in patients with the following: Gastrointestinal bleeding. Obstruction. Perforation.
What is the best prescription medication for nausea?
Prochlorperazine (or brand name Stemetil®) is one of the most used medicines for nausea. It works for many common causes of nausea, including vertigo, ear problems and sickness in pregnancy. Metoclopramide – this medicine works directly on your gut.
What are metoclopramide used for?
Metoclopramide is an anti-sickness medicine (known as an antiemetic). It’s used to help stop you feeling or being sick (nausea or vomiting) including: after radiotherapy or chemotherapy (treatment for cancer) sickness you may get with a migraine.
What does metoclopramide do to the body?
Metoclopramide is used to treat the symptoms of slow stomach emptying (gastroparesis) in patients with diabetes. It works by increasing the movements or contractions of the stomach and intestines. It relieves symptoms such as nausea, vomiting, heartburn, a feeling of fullness after meals, and loss of appetite.
What is Reglan prescribed for?
It is used mostly for heartburn that occurs after a meal or during the daytime. Treating ongoing heartburn can decrease the damage done by stomach acid to the swallowing tube (esophagus) and help healing. Metoclopramide is also used in diabetic patients who have poor emptying of their stomachs (gastroparesis).
How does metoclopramide help with GERD?
In patients with gastroesophageal reflux disease (GERD), a weakened lower esophageal sphincter allows reflux of stomach acid into the esophagus, causing heartburn and damage to the esophagus (esophagitis). Metoclopramide decreases the reflux of stomach acid by strengthening the muscle of the lower esophageal sphincter.
Is metoclopramide good for diarrhea?
diarrhoea (with high doses of metoclopramide) – drink lots of fluids, such as water or squash, to avoid dehydration. Signs of dehydration include peeing less than usual or having dark, strong-smelling pee. Do not take any other medicines to treat diarrhoea without speaking to a pharmacist or doctor.
What class of drug is metoclopramide?
Metoclopramide belongs to classes of drugs called antiemetics and prokinetics. Antiemetics are used to reduce nausea and vomiting, and prokinetics are used to empty the contents of your stomach faster. A class of drugs is a group of medications that work in a similar way. These drugs are often used to treat similar conditions.
How many times can metoclopramide be given in a day?
When metoclopramide injection is used to treat slowed stomach emptying due to diabetes, it may be given up to four times a day. When metoclopramide injection is used to prevent nausea and vomiting due to chemotherapy, it is usually given 30 minutes before the chemotherapy, then once every 2 hours for two doses,…
What should I know before taking metoclopramide?
Before you take metoclopramide, tell your doctor if you have kidney or liver disease, congestive heart failure, high blood pressure, diabetes, Parkinson’s disease, or a history of depression. Do not drink alcohol. It can increase some of the side effects of metoclopramide.
Can metoclopramide injection be given during surgery?
Metoclopramide injection is also sometimes given during surgery. If you are injecting metoclopramide injection at home, inject it at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.