What is Epileptogenic abnormality?
The epileptogenic lesion is defined as the structural abnormality that is presumed to be the basis of the seizures. Most commonly the lesion is a marker for the underlying epilepsy and may vary from gross to subtle and from strictly circumscribed to more diffuse.
What does Epileptogenic potential mean?
Epileptogenesis is defined as the process during which changes occur in the brain after a precipitating injury or insult that results in the development of spontaneous recurrent seizure activity or epilepsy. From: Neural Circuit Development and Function in the Brain, 2013.
What is electrographic seizure pattern?
Definition. Electrographic seizures. Rhythmic discharge or spike and wave pattern with definite evolution in frequency, location, or morphology lasting at least 10 s; evolution in amplitude alone did not qualify. Periodic epileptiform discharges.
Can an ECG detect epilepsy?
An ECG may identify people with epilepsy with silent coronary artery disease who may require further intervention to reduce their risks of heart attack or heart failure.
What is the Epileptogenic zone?
The epileptogenic zone is defined as the region of the brain from which the patient’s habitual seizures arise.
What is left hippocampal sclerosis?
Hippocampal sclerosis is characterized pathologically by loss of pyramidal neurons, granule cell dispersion and gliosis in the hippocampus. It can be associated with changes in nearby structures, known as mesial temporal sclerosis. It a common cause of temporal lobe seizures that do not respond to medication.
What is the best test for epilepsy?
Electroencephalogram (EEG). This is the most common test used to diagnose epilepsy. In this test, electrodes are attached to your scalp with a paste-like substance or cap. The electrodes record the electrical activity of your brain.
Can a blood test show epilepsy?
An epilepsy blood test measures the amount of the hormone prolactin in the blood. It helps determine whether a seizure was caused by epilepsy or another disorder.
What is the epileptogenic zone?
Because the epileptogenic zone is in fact a theoretical concept, preoperative evaluation is focused on identifying instead five well-defined cortical areas involved in seizure activity.
Can the epileptogenic zone be resurrected?
In patients in whom the epileptogenic zone cannot be resected, increasing use of the vagus nerve stimulator and other stimulation techniques, such as deep-brain stimulation, is likely in the future. All these treatments require the definition of the epileptogenic zone, which is, as mentioned above, a theoretical concept.
Can neuropsychological testing lateralize or localize the epileptogenic zone?
We now seldom rely on the results of neuropsychological testing to lateralize or localize the epileptogenic zone.
How are magnetoencephalographic epileptic foci confirmed in right frontocentral epilepsy?
Confirmation of two magnetoencephalographic epileptic foci by invasive monitoring from subdural electrodes in an adolescent with right frontocentral epilepsy. –13. Pacia SV, Jung WJ, Devinsky O. Localization of mesial temporal lobe seizures with sphenoidal electrodes.