What is the post exposure management for HBV?

Post-exposure prophylaxis (PEP) is treatment that can be used after possible exposure to the hepatitis B virus through sex, drug injecting equipment or injury such as needle stick injury. PEP is given to decrease the risk of infection with the hepatitis B virus.

When should HBIG be given after exposure?

HBIG should be given as soon as possible, preferably within 12 hours for perinatal exposure and within 24 hours for percutaneous or mucosal exposure. PEP is unlikely to be beneficial if initiated 7 days after percutaneous exposure or 14 days after sexual exposure. HBIG x1 and 1 dose of HB vaccine.

What is the treatment plan for a HBV PT?

Treatment for chronic hepatitis B may include: Antiviral medications. Several antiviral medications — including entecavir (Baraclude), tenofovir (Viread), lamivudine (Epivir), adefovir (Hepsera) and telbivudine (Tyzeka) — can help fight the virus and slow its ability to damage your liver.

What should I do if I have been exposed to hepatitis B?

If you know you’ve been exposed to hepatitis B, contact your doctor immediately. A preventive treatment may reduce your risk of infection if you receive the treatment within 24 hours of exposure to the virus. If you think you have signs or symptoms of hepatitis B, contact your doctor.

When should I take PEP medication?

PEP (post-exposure prophylaxis) means taking medicine to prevent HIV after a possible exposure. PEP should be used only in emergency situations and must be started within 72 hours after a recent possible exposure to HIV.

How do you do post-exposure prophylaxis?

PEP is a combination of three drugs. You take them once or twice a day for 28 days: For adults, the CDC recommends tenofovir, emtricitabine (these two drugs come in one pill), and a third drug, either raltegravir or dolutegravir.

Can hepatitis B vaccine be given after exposure to HBV?

Can hepatitis B vaccine be given after exposure to HBV? Yes. After a person has been exposed to HBV, appropriate prophylaxis, given as soon as possible but preferably within 24 hours, can effectively prevent infection.

How soon after exposure can you test for hepatitis B?

Experts call this the incubation period. Hepatitis B symptoms can take 60–150 days to develop, and a test can detect the virus after 1–9 weeks following exposure.

When should hepatitis B treatment start?

Current guidelines recommend initiating antiviral therapy in HBeAg-positive patients who have ALT levels ≥2 times the upper limit of normal (ULN) and HBV DNA levels ≥20,000 IU/ml.

What is the treatment for viral hepatitis?

About 25 percent of people with chronic hepatitis B can be cured with a drug called pegylated interferon-alpha, which is taken as a weekly injection for six months. The alternative is suppression of the virus with oral medications, such as lamivudine and adefovir.

What drugs are used for post-exposure prophylaxis?