What was metronidazole originally used for?

HISTORY OF METRONIDAZOLE USE: PARASITES CAME FIRST were screened for activity against Trichomonas vaginalis, a cause of vaginal itching. Azomycin, a nitroimidazole, was identified, and metronidazole, a synthetic derivative, was used to treat chronic trichomonad infections, beginning in 1959 (66).

What is metronidazole 500 mg used for UTI?

Descriptions. Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis). Metronidazole belongs to the class of medicines known as antibiotics.

How does metronidazole get rid of bacteria?

Metronidazole diffuses into the organism, inhibits protein synthesis by interacting with DNA and causing a loss of helical DNA structure and strand breakage. Therefore, it causes cell death in susceptible organisms.

How many days does it take metronidazole to work?

Metronidazole starts to work 1 to 2 hours after you take it, because it is quickly absorbed, and it reaches its maximum concentration after 20 minutes to 3 hours. But it may take a couple of days before you start to feel better or notice an improvement in your symptoms.

What foods should you avoid while taking metronidazole?

Alcohol, avocados, bananas, chocolate, salami

• Do not mix these items with drugs such as metronidazole (Flagyl) and linezolid (Zyvox), used to treat bacterial infections.
• These foods, along with tap beer, red wine, and sherry, contain tyramine, an amino acid that can cause blood pressure to spike if taken with linezolid.

Will metronidazole treat a yeast infection?

Metronidazole vaginal is used to treat women with vaginal infections (eg, bacterial vaginosis). Metronidazole belongs to the class of medicines known as antibiotics. It works by killing the bacteria or preventing their growth. However, this medicine will not work for vaginal fungus or yeast infections.

Can metronidazole be taken on an empty stomach?

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack. The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Is the ciliated protozoan parasite Cryptocaryon irritans in Taiwan?

1 Department of Zoology, National Taiwan University, Taipei 106, Taiwan, ROC. The ciliated protozoan parasite Cryptocaryon irritans infecting marine fishes in Taiwan is described.

How does Cryptocaryon irritans interact with Lates calcarifer?

Cryptocaryoniasis (also known as marine white spot disease) is mediated by Cryptocaryon irritans. This obligate ectoparasitic protozoan infects virtually all marine teleosts, which includes Lates calcarifer, a highly valuable aquaculture species. Little is known about L. calcarifer-C. irritans interactions.

Is Cryptocaryon irritans infecting marine fishes in Taiwan?

The ciliated protozoan parasite Cryptocaryon irritans infecting marine fishes in Taiwan is described. Developmental characteristics and sequences of the ribosomal DNA regions such as part of 18 S, the entire first internal transcribed spacer, and part of 5.8 S of various Taiwan isolates of C. irritans were investigated.