How do you root a MEGA phylogenetic tree?

If you have calculated your tree in MEGA5 or 6 you can select the branch that covers your outgroup (cluster) and select on the left hand menue the tab with the green arrow head for “place root on branch”. This will place the selected cluster at the bottom of your tree…

What is MEGA what are its applications?

MEGA (a recursive acronym standing for MEGA Encrypted Global Access) is a cloud storage and file hosting service offered by MEGA Limited, a company based in Auckland, New Zealand. The service is offered through web-based apps. MEGA mobile apps are also available for Android and iOS.

What is MEGA NCBI?

Abstract. A computer program package called MEGA has been developed for estimating evolutionary distances, reconstructing phylogenetic trees and computing basic statistical quantities from molecular data. It is written in C++ and is intended to be used on IBM and IBM-compatible personal computers.

What are molecular phylogenies based on?

Molecular phylogeny is a relatively new scientific discipline that involves the comparative analysis of the nucleotide sequences of genes and the amino acid sequences and structural features of proteins from which evolutionary histories and relationships, and in some cases also functions, can be inferred.

How do you make a phylogenetic tree?

Building a phylogenetic tree requires four distinct steps: (Step 1) identify and acquire a set of homologous DNA or protein sequences, (Step 2) align those sequences, (Step 3) estimate a tree from the aligned sequences, and (Step 4) present that tree in such a way as to clearly convey the relevant information to others …

How do I install mega 7 software?

The preferred way to install MEGA is to download the installer directly from the website ( Then run the installation program which will install MEGA in the location (directory) you specify.