What does ATP binding cassette do?

ATP-binding cassette (ABC) transporters are a large superfamily of membrane proteins with diverse functions (Holland et al. 2003). They convert the energy gained from ATP hydrolysis into trans-bilayer movement of substrates either into the cytoplasm (import) or out of the cytoplasm (export).

Where is the ATP binding cassette?

The NBD or ATP-binding cassette (ABC) domain, on the other hand, is located in the cytoplasm and has a highly conserved sequence.

What are ATP binding sites?

The ATP binding site is the environment in which ATP catalytically actives the enzyme and, as a result, is hydrolyzed to ADP. The binding of ATP causes a conformational change to the enzyme it is interacting with.

What are ATP dependent transporters?

ATP-binding cassette (ABC) transporters are an example of ATP-dependent pumps. ABC transporters are ubiquitous membrane-bound proteins, present in all prokaryotes, as well as plants, fungi, yeast and animals. These pumps can move substrates in (influx) or out (efflux) of cells.

What is a half transporter?

Some ABC genes encode proteins that are ‘half-transporters’ (meaning that two subunits bind as homodimers or a heterodimer), whereas others are ‘full-transporters’.

Is example of ATP-binding cassette?

What are actin binding sites?

Two diametrically opposed clefts separate the two large domains of actin. The larger cleft, between subdomains 2 and 4, constitutes the nucleotide-binding site, whereas the smaller cleft, between subdomains 1 and 3, mediates the interactions of actin with most ABPs (Fig. 1B).

Which of the following has ATP binding site?

So, the correct answer is ‘Head part of meromyosin’.

What are Antiporters and Symporters?

Symporters and antiporters are involved in active transport. Antiporters transport molecules in opposite directions, while symporters transport molecules in the same direction.