What are the indications for TAVR?

TAVR is indicated in patients with severe symptomatic aortic stenosis who are not suitable for SAVR as assessed by a Heart Team and who are likely to gain improvement in their quality of life and to have a life expectancy of >1 year after consideration of their comorbidities (PARTNER IB; class I, LoE B).

Who is a candidate for the TAVR procedure?

For TAVR to be recommended, the evaluation must confirm the following: You have aortic stenosis that is severe in nature and is causing symptoms. You are not a candidate for surgical aortic valve replacement or you’re at high risk for surgery and likely would benefit from TAVR therapy.

What is Edwards Sapien valve?

The Edwards SAPIEN 3 and SAPIEN 3 Ultra Transcatheter Heart Valve (THV) System is a catheter-based artificial heart valve system designed to replace a diseased heart valve without open-heart surgery. The valve is made of cow tissue attached to a balloon-expandable, cobalt-chromium frame for support.

Who is eligible for transcatheter aortic valve replacement?

Indications for aortic valve replacement (surgical or transcatheter) are as follows: Severe high-gradient AS with symptoms (class I recommendation, level B evidence) Asymptomatic patients with severe AS and LVEF < 50 (class I recommendation, level B evidence)

What is the criteria for aortic valve replacement?

Inclusion Criteria

  • Patient has severe aortic valve stenosis per echo: mean gradient >40 mmHg or jet velocity greater than 4.0m/s and an aortic valve area of <0.8 cm2 or indexed EOA <0.5 cm2/m2.
  • NYHA >2.
  • Probability of death or serious, irreversible morbidity >50%

Who Cannot get a TAVR?

“A potential TAVR candidate must have severe aortic stenosis and a three-leaflet valve versus a two-leaflet valve (bicuspid aortic valve).” Patients with endocarditis (infection of the heart) or associated aneurysms are also not candidates.

Who should not get TAVR?

Contraindications (Who should not use): The Edwards SAPIEN 3 and Edwards SAPIEN 3 Ultra Transcatheter Heart Valve System should not be used in patients who: Cannot tolerate medications that thin the blood or prevent blood clots from forming. Have an active infection in the heart or elsewhere.

Is Edwards Sapien valve mechanical?

What is it? The Edwards SAPIEN 3 and SAPIEN 3 Ultra Transcatheter Heart Valve (THV) System each consists of a catheter-based artificial aortic heart valve and the accessories used to implant the valve without open-heart surgery.

What type valve is used in Tavr?

Transcatheter aortic valve replacement (TAVR) is a minimally invasive heart procedure to replace a thickened aortic valve that can’t fully open (aortic valve stenosis). The aortic valve is located between the left lower heart chamber (left ventricle) and the body’s main artery (aorta).