Who should not take N-Acetyl L Cysteine?

People who have bleeding disorders or take blood thinning medications should not take NAC, because it may slow blood clotting ( 49 ). NAC has an unpleasant smell that makes it hard to consume. If you choose to take it, consult your doctor first.

What are the side effects of N-acetyl L cysteine?

N-acetyl cysteine is an FDA-approved prescription drug. It can cause side effects such as dry mouth, nausea, vomiting, and diarrhea. It has an unpleasant odor that some people find hard to tolerate.

What is N-Acetyl L Cysteine good for?

N-acetyl cysteine (NAC) is used by the body to build antioxidants. Antioxidants are vitamins, minerals, and other nutrients that protect and repair cells from damage. You can get NAC as a supplement or a prescription drug.

Can NAC be harmful?

NAC may raise levels of homocysteine, an amino acid that is associated with heart disease. Be sure to have your doctor check your homocysteine level if you are taking NAC. Very high doses (more than 7 grams) of cysteine may be toxic to human cells and may even lead to death.

Why is N acetyl cysteine banned?

In July 2020, FDA sent warning letters to companies declaring that NAC is not a lawful dietary ingredient per the FD&C Act’s drug-exclusion clause because the ingredient was first authorized for investigation as a new drug before it was marketed as a dietary supplement.

Does N-acetylcysteine raise blood pressure?

Results: No significant changes in blood pressure, albuminuria and homocysteine plasma level were observed. Conclusions: NAC had no effect on blood pressure and surrogate markers of cardiovascular injury in non-diabetic patients with CKD.

What time of day is best to take NAC?


  • Examples: 5HTP, Methionine and SAMe, N- Acetyl Cysteine (NAC) , Tyrosine and Glycine.
  • When to take: On an empty stomach eg 30min before breakfast on rising or 2 hours after dinner at bedtime.
  • Examples: Vitamins A/B/C/D/E.
  • When to take: With food, see below.

Can NAC cause joint pain?

Results. Our study sample comprised 12,928 people who used NAC and 51,715 NAC nonusers. NAC users had a significantly higher incidence of osteoarthritis (adjusted hazard ratio: 1.42, P < . 001) than did NAC nonusers.