Can fluconazole cause fixed drug eruption?
On rare occasions, fluconazole has been shown to cause fixed drug eruptions. Lesions of fixed drug eruptions vary in size and number, but have the same general appearance and symptoms. The authors report a case of fluconazole-induced fixed drug eruption in a 24-year-old woman with recurrent vaginal candidiasis.
How do you treat allergic reaction to fluconazole?
You do not need to be concerned unless you start feeling symptoms of an allergic reaction: swelling of your face, lips, tongue, or throat, hives or difficulty breathing; in which case you should get to an emergency department immediately. Your pharmacist will be able to suggest an effective treatment for your rash.
How long does it take for a fixed drug eruption to heal?
The FDEs were treated by discontinuing the offending drug, topical corticosteroids, and oral antihistamines. More than half (50.4%) of the patients recovered within 10 days, while in 14 patients, the lesions took between 11 and 30 days to resolve.
What drugs cause fixed eruptions?
The major categories of causative agents of fixed drug eruption include antibiotics, antiepileptics, nonsteroidal anti-inflammatory agents, sildenafil, and phenothiazines, although numerous other agents and certain foods such as cashews and licorice have also been reported as causative agents.
How do you treat fixed drug eruption on lips?
The main goal of treatment is to identify the causative agent and avoid it. Treatment for fixed drug eruptions (FDEs) otherwise is symptomatic. Systemic antihistamines and topical corticosteroids may be all that are required. In cases in which infection is suspected, antibiotics and proper wound care are advised.
How are drug eruptions treated?
Treatment includes identifying and withdrawing the offending agent as soon as possible. A biopsy may be helpful in establishing a diagnosis of a drug reaction. For mild drug eruptions, treatment is supportive with anti-histamines, topical steroids, and moisturizing lotions.
How are fixed drug eruptions treated?
Treatment for fixed drug eruptions (FDEs) otherwise is symptomatic. Systemic antihistamines and topical corticosteroids may be all that are required. In cases in which infection is suspected, antibiotics and proper wound care are advised.
How long does it take to have an allergic reaction to fluconazole?
Swelling and redness of skin are typically seen within 30 minutes to eight hours after exposure.
Is fixed drug eruption serious?
Fixed drug eruption is generally a benign self-resolving eruption that recurs on re-exposure, leaving post-inflammatory hyperpigmentation. Subsequent flares can be more severe. Generalised bullous fixed drug eruption can be life-threatening, and has been reported to have a 20% mortality rate.
How do fixed drug eruptions heal?
How long does a drug eruption last?
Most patients with mild drug eruptions should expect clearing in approximately 1-2 weeks with no complications. All patients should be educated to avoid the offending agent to prevent further complications.