Which vitamin is used as cofactor?

Vitamins and derivatives

Cofactor Vitamin Chemical group(s) transferred
Coenzyme A Pantothenic acid (B5) Acetyl group and other acyl groups
Tetrahydrofolic acid Folic acid (B9) Methyl, formyl, methylene and formimino groups
Menaquinone Vitamin K Carbonyl group and electrons
Ascorbic acid Vitamin C Electrons

What are cofactors and coenzymes give examples?

Typically, cofactors are metal ions. Some metallic elements have no nutritional value, but several trace elements function as cofactors in biochemical reactions, including iron, copper, zinc, magnesium, cobalt, and molybdenum.

What are coenzymes vs cofactors?

Coenzymes are organic molecules and quite often bind loosely to the active site of an enzyme and aid in substrate recruitment, whereas cofactors do not bind the enzyme. Cofactors are “helper molecules” and can be inorganic or organic in nature.

Is vitamin Ka coenzyme or cofactor?

Abstract. Vitamin K is a cofactor for the synthesis of blood coagulation Factors II, VII, IX and X, and inhibitors such as Protein C and S and bone matrix protein. Its active form is a coenzyme in the glutamic acid carboxylation.

Are coenzymes a type of cofactor?

A coenzyme is one type of cofactor. Coenzymes are organic molecules required by some enzymes for activity. A cofactor can be either a coenzyme or an inorganic ion.

Are all coenzymes vitamins?

Most coenzymes are vitamins or are derived from vitamins. Vitamins are organic compounds that are essential in very small (trace) amounts for the maintenance of normal metabolism….Learning Objectives.

Vitamin biotin
Coenzyme biotin
Coenzyme Function carboxylation reactions
Deficiency Disease

Which vitamins are coenzymes?


  • All of the water-soluble vitamins and two of the fat-soluble vitamins, A and K, function as cofactors or coenzymes.
  • The active forms of riboflavin, vitamin B2, are the coenzymes flavin mononucleotide (FMN; Figure 2) and flavin adenine dinucleotide (FAD).

Is zinc a cofactor or coenzyme?

Zinc is a cofactor for up to 300 enzymes in the body1. Enzymes that use zinc as a cofactor are known as metalloenzymes. Zinc is a cofactor for the antioxidant enzyme superoxide dismutase that converts superoxide to hydrogen peroxide, as shown below.

Is biotin a cofactor or coenzyme?

Biotin is a water-soluble vitamin and serves as a coenzyme for five carboxylases in humans.

What do cofactors do?

Cofactors can be metals or small organic molecules, and their primary function is to assist in enzyme activity. They are able to assist in performing certain, necessary, reactions the enzyme cannot perform alone. They are divided into coenzymes and prosthetic groups.