What are subgroup effects?

Subgroup analyses are common and often associated with claims of difference of treatment effects between subgroups—termed “subgroup effect”, “effect modification”, or “interaction between a subgroup variable and treatment”.

What is subgroup analysis in clinical trials?

By “subgroup analysis,” we mean any evaluation of treatment effects for a specific end point in subgroups of patients defined by baseline characteristics. The end point may be a measure of treatment efficacy or safety.

What is the purpose of subgroup analysis?

Subgroup analysis is one way of finding out. It’s a type of analysis done by breaking down study samples into subsets of participants based on a shared characteristic. The goal is to explore differences in how people respond to an intervention.

What is the purpose of a subgroup?

The main aim of a subgroup analysis is to identify either consistency of or large differences in the magnitude of treatment effect among different categories of patients.

What are subgroups in statistics?

What is a subgroup? A subgroup is a group of units that are created under the same set of conditions. Subgroups (or rational subgroups) represent a “snapshot” of the process. Therefore, the measurements within a subgroup must be taken close together in time but still be independent of each other.

What is subgroup in quality control?

A rational subgroup is a group of units produced under the same set of conditions. Rational subgroups are meant to represent a “snapshot” of the process. They also reflect how your data are collected, and represent the inherent (common cause) variation in your process at any given time.

What are subgroups in research?

Subgroup analyses involve splitting all the participant data into subgroups, often so as to make comparisons between them. Subgroup analyses may be done for subsets of participants (such as males and females), or for subsets of studies (such as different geographical locations).

What is a subgroup meta-analysis?

In a subgroup analysis, all participant data included in the meta-analysis is split into subgroups, according to patient characteristics (such as gender) or trial characteristics (such as geographical location), and a meta-analysis is then performed on one or more of these subsets.

What are subgroups in control charts?

A subgroup is a group of units that are created under the same set of conditions. Subgroups (or rational subgroups) represent a “snapshot” of the process. Therefore, the measurements within a subgroup must be taken close together in time but still be independent of each other.

What is a subgroup in Six Sigma?

Rational Subgrouping is the name given to the way in which data are organized into subgroups for process control charts. Rational subgroups for process control charts involve the use of process and product knowledge and judgment, but there are a few basic principles that should be followed.